SBM 202 | Course Introduction and Application Information - Medicine

Course Name

Scientific Basis of Medicine IV

Code	Semester	Theory (hour/week)	Application/Lab (hour/week)	Local Credits	ECTS
SBM 202	Spring	16	4	18	18

Prerequisites	None
Course Language	English
Course Type	Required
Course Level	First Cycle
Mode of Delivery	face to face
Teaching Methods and Techniques of the Course	Discussion Group Work Problem Solving Case Study Q&A Critical feedback Jury Simulation Field trip / Observation Application: Experiment / Laboratory / Workshop Lecture / Presentation
National Occupation Classification	-
Course Coordinator	Prof. Dr. Metiner Tosun
Course Lecturer(s)	Doç. Dr. Ayşe Banu DEMİR Doç. Dr. Barış Emre DAYANÇ Doç. Dr. Can KARACA Doç. Dr. Özden GÖKDEMİR Doç. Dr. Yasemin SEVAL ÇELİK Dr. Öğr. Üyesi Ali Burak ÖZKAYA Dr. Öğr. Üyesi Elif BARIŞ Dr. Öğr. Üyesi Melis KARTAL YANDIM Dr. Öğr. Üyesi Özge ERTENER Öğr. Gör. Dr. Önder Küçük Prof. Dr. Ayşın ZEYTİNOĞLU TÜRKEŞ Prof. Dr. Gönül DİNÇ HORASAN Prof. Dr. Gül AKDOĞAN Prof. Dr. Gülfem ECE Prof. Dr. Kamer MUTAFOĞLU Prof. Dr. Metiner TOSUN Prof. Dr. Zübeyde ERBAYRAKTAR
Assistant(s)	Araş. Gör. Yağmur ÖZBEK İŞBİTİREN

Course Objectives	In this course; relevant topics in pharmacology, medical microbiology, immunology, basic pathology and epidemiology will be discussed. This course aims to form a basis for the pathological phase where pathophysiological mechanisms of diseases, diagnosis and treatment will be learned.
Learning Outcomes	The students who succeeded in this course; Explain the phases of drug development and their features, classification of the drugs; the drug and the body interaction and the factors altering this interaction Describe the major determinants of infectious diseases, the links in the “chain of infection” and the role of correct diagnosis, treatment and appropriate infection control measures for breaking the links Define the main microbiological features of medically important pathogens Explain cellular and molecular components and associated mechanisms of innate and adaptive immune responses that protect our body from infections or cancer Explain the causes and mechanisms of reversible, irreversible cell injury and cellular adaptation Describe the mechanisms of inflammation, define its types and associated morphologic features Define the mechanisms of tissue repair, the factors influencing the tissue repair, the differences between primary and secondary wound healing Explain the mechanisms of hemodynamic disorders, thrombus, embolism, infarction and their morphological features Define the shock types, their pathogenesis, morphological and clinical features Explain the basic processes underlying the transformation of a normal cell to its malignant form, and the consequences of malignant transformation on the cellular and organism level Define the basic nomenclature, morphologic characteristics, grading and staging of tumors, and the principles of tumor diagnosis and treatment. Explicate the basic principles of imaging and clinical laboratory methods and their clinical applications. Define the characteristics of different stages of healthy life from childhood to the end-of-life, the lifecycle related health risks and preventive measures Explain how the basic concepts in epidemiology and biostatistics are applied to causal factors for health problems. Evaluate their own reflection, self-assessment and feedback skills, identify their strengths and weaknesses, create a development plan for the aspects that need to be improved, and present the portfolio evidences in a file.
Course Description	• Basic principles of pharmacology including pharmacokinetics and pharmacodynamics • Basic concepts of infection, infection control, pathogenesis and microbiology of medically important microorganisms • Molecular and cellular components and pathways of innate and adaptive immune responses against infections or cancer. • Injurious agents interfering with homeostasis • The concept and mechanisms of disease and corresponding alterations occurring in the body • The impact of biopsychosocial and cultural factors on human health • General features of the related laboratory and clinical diagnostic procedures. • Changing health needs and challenges along the human life cycle and prepare them to anticipate and address the health issues at different stages of life in the clinical setting. • Basic principles of therapy.
Related Sustainable Development Goals

Course Category	Core Courses	X
	Major Area Courses
	Supportive Courses
	Media and Management Skills Courses
	Transferable Skill Courses

Week	Subjects	Related Preparation
1	Pharmacology (Pharmacokinetics, Pharmacodynamics), Infection Basics, Introduction to Immune response	Weekly course material (Lecture presentations, study material such as online Reference Book chapters, Lecturio videos etc.) uploaded by the instructor to BlackBoard Learn. Please also check the material listed in following Study Notes / Texbook section.
2	Pharmacology (Quantitative evaluation of drug –receptor interactions, Antimicrobials), Basic concepts in bacteriology, molecular basis of adaptive immunity, Research Information Management	Weekly course material (Lecture presentations, study material such as online Reference Book chapters, Lecturio videos etc.) uploaded by the instructor to BlackBoard Learn. Please also check the material listed in following Study Notes / Texbook section.
3	Molecular basis of adaptive immunity, Fungal infections, Diagnostic sensitivity (RIM), Diagnosis of bacterial infections	Weekly course material (Lecture presentations, study material such as online Reference Book chapters, Lecturio videos etc.) uploaded by the instructor to BlackBoard Learn. Please also check the material listed in following Study Notes / Texbook section.
4	Antibodies, Mycology, epidemiology, Antifungals, Bayesian theory (RIM), Pharmacology. Discussion sessions & Midterm Exam I	Weekly course material (Lecture presentations, study material such as online Reference Book chapters, Lecturio videos etc.) uploaded by the instructor to BlackBoard Learn. Please also check the material listed in following Study Notes / Texbook section.
5	Bacteriology, Virology, Adaptive immunity	Lecture presentations and study material (online Reference Book chapters, Lecturio videos etc.) uploaded by the instructor to BlackBoard Learn. Please also check the material listed in following Study Notes / Texbook section.
6	Bacteriology (Testing), Viral pathogenesis, Adaptive Immunity, Pharmacology	Weekly course material (Lecture presentations, study material such as online Reference Book chapters, Lecturio videos etc.) uploaded by the instructor to BlackBoard Learn. Please also check the material listed in following Study Notes / Texbook section.
7	Bacteriology, Pharmacology	Weekly course material (Lecture presentations, study material such as online Reference Book chapters, Lecturio videos etc.) uploaded by the instructor to BlackBoard Learn. Please also check the material listed in following Study Notes / Texbook section.
8	Bacteriology, Hypothesis tests (RIM), Reference intervals (Lab Medicine). Discussion Sessions & Midterm Exam 2	Weekly course material (Lecture presentations, study material such as online Reference Book chapters, Lecturio videos etc.) uploaded by the instructor to BlackBoard Learn. Please also check the material listed in following Study Notes / Texbook section.
9	DNA damage, Aging, Cell signaling and disease (Medical Biol), Regression analyses (RIM), Biochemical mechanisms of diseases (Biochem), Cellular growth and differentiation (Pathology), Inflammation and Immunity (Immunology),	Weekly course material (Lecture presentations, study material such as online Reference Book chapters, Lecturio videos etc.) uploaded by the instructor to BlackBoard Learn. Please also check the material listed in following Study Notes / Texbook section.
10	Inflammation, Wound healing, Tissue repair Adaptation and cell injury(Pathology), NSAIDs (Pharmacology), Genetic factors & thrombosis (Medical Biol)
11	Hypovolemic shock (Gen. Surgery), Virology (Microbiol), Embolism (Pathology)	Weekly course material (Lecture presentations, study material such as online Reference Book chapters, Lecturio videos etc.) uploaded by the instructor to BlackBoard Learn. Please also check the material listed in following Study Notes / Texbook section.
12	1-day National Holiday (May 1), Wound healing and oxydative stress (Biochem), Autoimmunity (Immunology), Autoimmune disease (Pathology), Virology (Microbiology), Antivirals (Pharmacology) Discussion Sessions & Midterm Exam 3	Weekly course material (Lecture presentations, study material such as online Reference Book chapters, Lecturio videos etc.) uploaded by the instructor to BlackBoard Learn. Please also check the material listed in following Study Notes / Texbook section.
13	Immunodefficiencies, vaccinations (Immunology), Discussion sessions.	Weekly course material (Lecture presentations, study material such as online Reference Book chapters, Lecturio videos etc.) uploaded by the instructor to BlackBoard Learn. Please also check the material listed in following Study Notes / Texbook section.
14	Oncoviruses (Microbiology), Immunosuppressants (Pharmacology), Case control studies (RIM), Carcinogenesis (Medical Biol, Histology & Embriology, Immunology)	Weekly course material (Lecture presentations, study material such as online Reference Book chapters, Lecturio videos etc.) uploaded by the instructor to BlackBoard Learn. Please also check the material listed in following Study Notes / Texbook section.
15	Carcinogenesis (Immunology, Pathology, Pathology), Infectious diseases (Public Health)	Weekly course material (Lecture presentations, study material such as online Reference Book chapters, Lecturio videos etc.) uploaded by the instructor to BlackBoard Learn. Please also check the material listed in following Study Notes / Texbook section.
16	Parasitology	Weekly course material (Lecture presentations, study material such as online Reference Book chapters, Lecturio videos etc.) uploaded by the instructor to BlackBoard Learn. Please also check the material listed in following Study Notes / Texbook section.
17	Growth and development (Pediatrics), Carcinogenesis models (Immunology), Lab Medicine, Pathology practicals, Psychosocial development (Psychiatry, Internal Medicine), Chemotherapeutics (Pharmacology), Nutrition (Pediatrics, Dietetics), Evaluation of well child (Pediatrics), Molecular diagnostics (Lab Medicine) Midterm Exam 4	Weekly course material (Lecture presentations, study material such as online Reference Book chapters, Lecturio videos etc.) uploaded by the instructor to BlackBoard Learn. Please also check the material listed in following Study Notes / Texbook section.
18	Life-cycle (Pediatrics, Internal Medicine, Family Medicine, Medical Biology, Public Health)	Weekly course material (Lecture presentations, study material such as online Reference Book chapters, Lecturio videos etc.) uploaded by the instructor to BlackBoard Learn. Please also check the material listed in following Study Notes / Texbook section.

Course Notes/Textbooks

1. 1. Basic and Clinical Pharmacology, McGraw-Hill Medical, 14th Edition. Bertram G. Katzung, 2018. https://accessmedicine.mhmedical.com/book.aspx?bookid=2249
  2. Goodman & Gilman’s Pharmacological Basis of Therapeutics, McGraw-Hill Medical 13^th Edition, Chapter 52. https://accessmedicine.mhmedical.com/content.aspx?bookid=2189&sectionid=172483986#1149954192
  3. Katzung & Trevor's Pharmacology: Examination & Board Review, 12th Edition. Bertram G. Katzung, Marieke Kruidering-Hall, Anthony J. Trevor, 2019. https://accessmedicine.mhmedical.com/book.aspx?bookid=2465
  4. Jawetz, Melnick & Adelberg's Medical Microbiology, 28e. https://accessmedicine.mhmedical.com/Book.aspx?bookid=2629
  5. Sherris & Ryan's Medical Microbiology, 8e. ttps://accessmedicine.mhmedical.com/Book.aspx?bookid=3107
  6. Abbas, Lichtman, Pillai Cellular and Molecular Immunology 8th Ed Elsevier Saunders, 2015.
  7. Review of Medical Microbiology & Immunology: A Guide to Clinical Infectious Diseases, 17th edition. https://accessmedicine.mhmedical.com/Book.aspx?bookid=3123
  8. Epidemiology, Evidence-based Medicine and Public Health, 6th edition. Yoav Ben-Shlomo, Sara Brookes, Matthew Hickman, 2013.
  9. Thomson & Thomson Genetics in Medicine, 8th Edition, Elsevier, 2016.
  10. Molecular Biology of the Cell Alberts, Johnson, Lewis, Raff, 2015.
  11. Thomson & Thomson Genetics in Medicine, 8th Edition, Elsevier Nussbaum R.L. 2016.
  12. Molecular Biology of Cancer, 4th Edition Lauren Pecorino 2016.
  13. Rubin's Pathology.7th Ed. Wolters Kluwer, 2015.
  14. Robbins Pathology, Vinay Kumar, Abul K. Abbas, Jon C. Aster-Robbins and Cotran. Pathologic Basis of Disease, Professional Edition-Saunders, 2014.
  15. Pathology: The Big Picture, Lange. https://accessmedicine.mhmedical.com/book.aspx?bookid=499
  16. Pathophysiology of Disease: An Introduction to Clinical Medicine, 8th edition.
  17. Clinical Biochemistry, An Illustrated Colour Text Gaw, Murphy, Srivastava 2013
  18. Harper’s Illustrated Biochemistry, 30th Ed.
  19. Lecture Notes: Epidemiology, Evidence-based Medicine and Public Health, 6th edition.
  20. Human Physiology/Development: birth through death. http://en.wikibooks.org/wiki/Human_Physiology/Development:_birth_through_death%23Adulthood.
  21. Disease Prevention & Health Promotion. Current Medical Diagnosis & Treatment. 56th ed. McGraw-Hill Education; Chp.1. https://accessmedicine.mhmedical.com/book.aspx?bookID=2449
  22. The year in cardiology 2018: prevention. European Heart Journal (2019) 40, 336–344. doi:10.1093/eurheartj/ehy894
  23. WHO/ Noncommunicable diseases and their risk factors/ STEPwise approach to chronic disease risk factor surveillance/ Country Fact Sheets(https://www.who.int/ncds/surveillance/steps/Factsheet-STEPS-Turkey-ENG-08.10.2018.pdf?ua=1)
  24. Determinants of Health and Health Inequities. AFMC Primer on Population Health. (2nd edition) The Association of Faculties of Medicine of Canada, Ottawa, p45-68. https://afmc.ca/AFMCPrimer.pdf?ver=1.2
  25. Human Sexuality from cells to society, Wadsworth Publishing Martha S. Rosenthal. 2013.
  26. Goldson E, Angulo AS, Reynolds A, Raz DM. Child Development & Behavior. In: Hay Jr. WW, Levin MJ, Abzug MJ, Bunik M. Current Diagnosis & Treatment: Pediatrics, 25e. McGraw-Hill. https://accessmedicine.mhmedical.com/content.aspx?bookid=2815&sectionid=24425560123.
  27. Haemer MA, Diab LK, Primak LE, Krebs NF. Normal Childhood Nutrition & Its Disorders. In: Hay Jr. WW, Levin MJ, Abzug MJ, Bunik M. Current Diagnosis & Treatment: Pediatrics, 25e. McGraw-Hill. https://accessmedicine.mhmedical.com/content.aspx?bookid=2815&sectionid=244257434
  28. Human Sexuality. 5th. Ed. Harper Collins College Publisher Masters W., Johnson V., Kolodny RC. 1995
  29. Cellular and molecular immunology. Eds. Abbas, Lichtman, Pillai. 10th ed. Elsevier, 2021. https://www.clinicalkey.com/#!/browse/book/3-s2.0-C20190004463
  30. Janeway's Immunobiology. Eds. Murphy, Weaver, Berg. 10th ed. Norton & Company, 2022.
  31. Chapel and Haeney's Essentials of Clinical Immunology. Eds. Misbah, Spickett, Dalm. 7th ed. Wiley Blackwell, 2022.
  32. Murray Patrick R. Ken S. Rosenthal and Michael A. Pfaller. 2016. Medical Microbiology 8th ed.. Philadelphia: Elsevier/Saunders.

Suggested Readings/Materials

- https://ieu.lecturio.com/#/lecture/c/6872/6660/22012 Phases of Drug Development
- https://ieu.lecturio.com/#/lecture/c/6872/6660/22000 Introduction to Pharmacokinetics (PK)
- https://ieu.lecturio.com/#/lecture/c/6872/6660/22002 Hydrophilic vs. Hydrophobic – PK
- https://ieu.lecturio.com/#/lecture/c/6872/6660/22006 pKa and Drug Solubility – PK
- https://ieu.lecturio.com/#/lecture/c/6872/6660/22008 Drug Distribution – PK
- https://ieu.lecturio.com/#/lecture/c/6872/6660/22014 Drug Metabolism – PK
- https://ieu.lecturio.com/#/lecture/c/6872/6660/22022 Factors Affecting Biotransformation-PK
- https://ieu.lecturio.com/#/lecture/c/6872/6660/22036 Drug Receptors and Effectors – Pharmacodynamics
- https://ieu.lecturio.com/#/lecture/c/6872/6660/22040 Dose-Response, – Pharmacodynamics
- https://ieu.lecturio.com/#/course/c/6432/8280 (Bacteria, videos 1- 8)
- https://ieu.lecturio.com/#/course/c/6432/8280 (Bacteria)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23516 Antimetabolites (Antibiotics)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23490 Cell Wall Synthesis Inhibitors (Antibiotics)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23504 Bacterial Protein Synthesis Inhibitors (Antibiotics)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23492 Penicillins – Cell Wall Synthesis Inhibitors (Antibiotics)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23496 Cephalosporins – Cell Wall Synthesis Inhibitors (Antibiotics)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23498 Penems – Cell Wall Synthesis Inhibitors (Antibiotics)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23502 Monobactams, Cyclic Lipopeptide and Polypeptide (Antibiotics)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/120757 Glycopeptide and Intracellular Agents (Antibiotics)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23506 Linezolid, Streptogramins and Chloramphenicol (Antibiotics)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23508 Macrolides and Ketolides (Antibiotics)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23510 Tetracyclines (Antibiotics)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23512 Aminoglycosides (Antibiotics)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23516 Antimetabolites (Antibiotics)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23518 Antimetabolites (Antibiotics)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23522 Antimycobacterial Agents
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23524 First-line Agents (Antimycobacterials)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/108980 Other Agents to Treat Tuberculosis (Antimycobacterials)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/108981 New Agents to Treat Tuberculosis (Antimycobacterials)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23526 Treatment Regimens for M.Tuberculosis (Antimycobacterials)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/120758 Treatments for Leprosy (Antimycobacterials)
- https://ieu.lecturio.com/#/course/c/6432/8284 (Fungi)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23538 Antifungals
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23540 Azoles (Antifungals)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23542 Polyenes (Antifungals)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23544 Flucytosine (Antifungals)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23548 Griseofulvin and Squalene Epoxidase Inhibitor (Antifungals)
- https://ieu.lecturio.com/#/course/c/6432/8282 (Virology)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/108984 Overview (Antivirals)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23576 Influenza Treatment (Antivirals)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23572 Thymidine Kinase Agents (Antivirals)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23574 RNA Polymerase Inhibitors (Antivirals)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23578 Hepatitis Treatment (Antivirals)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23580 Treatment of CMV Retinitis (Antivirals)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/108985 Anti-HIV Agents (Antivirals)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/108986 CCR5 – Antivirals
- https://ieu.lecturio.com/#/lecture/c/6872/6956/108987 Anti-HIV Agents: Entry Inhibitors (Antivirals)
- https://ieu.lecturio.com/#/course/c/6432/8286 (Parasitology)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23670 Antimalarial Drugs (Antiprotozoals)
- https://ieu.lecturio.com/#/lecture/c/6872/6956/23672 Amebicides (Antiprotozoals)
- https://ieu.lecturio.com/#/course/c/6890/6662 (Immune system: Overview and Cells)
- https://ieu.lecturio.com/#/course/c/6890/6896 (Innate Immune system)
- https://ieu.lecturio.com/#/course/c/6890/6898 (Adaptive Immune system)
- https://ieu.lecturio.com/#/course/c/6890/6900 (Humoral and Cell mediated Immunity)
- https://ieu.lecturio.com/#/course/c/6890/6902 (Immunedeficiency and immune deficiency diseases)
- https://ieu.lecturio.com/#/course/c/6890/6904 (Hypersensitivity and Autoimmune diseases)
- https://ieu.lecturio.com/#/course/c/40695 (cellular injury)
- https://ieu.lecturio.com/#/course/c/40696 (inflammation)
- https://ieu.lecturio.com/#/lecture/c/6872/6920/23144 Pharmacology of Inflammation
- https://ieu.lecturio.com/#/lecture/c/6872/6920/23148 Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
- https://ieu.lecturio.com/#/lecture/c/6872/6920/23146 Acetylsalicylic Acid (ASA
- https://ieu.lecturio.com/#/lecture/c/6872/6920/23150 COX-2 Inhibitors
- https://ieu.lecturio.com/#/course/c/7512 (neoplasia)

Semester Activities	Number	Weigthing
Participation
Laboratory / Application
Field Work
Quizzes / Studio Critiques
Portfolio	1	10
Homework / Assignments	1	10
Presentation / Jury
Project
Seminar / Workshop
Oral Exams
Midterm	4	40
Final Exam	1	40
Total

Weighting of Semester Activities on the Final Grade	6	60
Weighting of End-of-Semester Activities on the Final Grade	1	40
Total

Semester Activities	Number	Duration (Hours)	Workload
Theoretical Course Hours (Including exam week: 18 x total hours)	18	16	288
Laboratory / Application Hours (Including exam week: '.18.' x total hours)	18	4	72
Study Hours Out of Class	18	4	72
Field Work			0
Quizzes / Studio Critiques			0
Portfolio	1	10	10
Homework / Assignments	2	5	10
Presentation / Jury			0
Project			0
Seminar / Workshop			0
Oral Exam			0
Midterms	4	10	40
Final Exam	1	40	40
		Total	532

#	Program Competencies/Outcomes	* Contribution Level
#	Program Competencies/Outcomes	1	2	3	4	5
1	Knowledge of medical practices: Utilizes knowledge from basic and clinical medical sciences, epidemiology, biostatistics, biomedical informatics, and social and behavioral sciences to prevent, diagnose, treat, and manage medical problems.	-	-	-	X	-
2	Competence in professional skills: Competence in Professional Skills: Possesses the basic medical skills and attitude necessary for practicing the profession, understands personal limits, evaluates own performance, identifies areas needing improvement, and implements these improvements within a plan.	-	X	-	-	-
3	Patient Management: Provides patient-centered, holistic, safe, reliable, fair, and evidence-based healthcare services, prioritizing the protection and promotion of health, especially for the primary health issues in the community. Seeks support from other healthcare professionals and institutions when necessary, following the referral chain.	-	-	-	-	-
4	Patient and Employee Safety: Delivers healthcare services with consideration for the health and safety of both patients and healthcare workers throughout diagnosis, treatment, and rehabilitation processes.	-	-	X	-	-
5	Planetary Health and Healthy Lifestyles: Considers the impact of the planet's resources on individual and community health in professional practices. Takes it as a duty to inform the public, promote healthy lifestyles, and eliminate factors that negatively affect health.	-	-	-	-	-
6	Information Management and Research: Explains the role and importance of scientific research and evidence in delivering high-quality and safe healthcare services. Analyzes health issues in the community using scientific methods. Utilizes information generated through research and accessed from accurate, reliable sources, by appropriately using information technologies, in evidence-based patient management processes.	X	-	-	-	-
7	Adherence to Ethical Principles: Fulfills duties and responsibilities within the framework of ethical principles, rights, and legal obligations required by the profession, considering good medical practices and deontology principles. Recognizes ethical dilemmas and can analyze and make decisions accordingly.	-	X	-	-	-
8	Professional Virtues: Avoids behaviors that could undermine public trust in the medical profession. Approaches patients with compassion, care, and empathy without discrimination, prioritizing their well-being over personal interests. Ensures the confidentiality and privacy of patient information.	-	-	-	-	-
9	Health Policies and Advocacy: Assesses the impact of health policies on the health indicators of individuals and communities. Advocates for the development of healthcare services in line with social reliability and responsibilities.	-	-	-	-	-
10	Protecting and Promoting Health as a Social Responsibility: Accepts the protection and promotion of community health as a social responsibility, identifies priority health issues in the community served, develops solutions, and provides health education and counseling services.	-	-	-	-	-
11	Protecting and Promoting Health in Extraordinary Situations: Prioritizes the protection and promotion of individual and community health during extraordinary situations. Performs clinical and public health practices in a comprehensive and competent manner.	-	-	-	-	-
12	Healthy Physician - Healthy Community: Pays attention to personal health, hygiene, safety, and appearance. Explains and implements measures for maintaining health, strategies for coping with stress, and preventing burnout to maintain a healthy life. Sets an example for colleagues and the community through personal practices.	-	-	X	-	-
13	Change Management and Leadership: Systematically identifies issues and processes requiring change to provide high-quality, safe, and cost-effective healthcare services, along with the necessary resources. Acquires the skills to lead these changes effectively.	-	-	-	-	-
14	Teamwork: Establishes positive communication with healthcare professionals and other occupational groups. Demonstrates effective feedback practices, adopts a supportive approach, understands and fulfills personal rights, duties, and responsibilities in a timely and appropriate manner, and takes on different team roles as needed.	-	-	-	-	-
15	Communication Skills: Effectively uses written, verbal, and non-verbal communication.	-	-	-	-	-
16	Communication for Qualified and Safe Healthcare: Engages with patients, their families, healthcare professionals, other occupational groups, institutions, and organizations to minimize patient safety risks, enhance the quality of healthcare, in clear, understandable, and professionally appropriate communication while involving patients in decision-making processes, and considering potential differences and needs while providing necessary information.	-	-	-	-	-
17	Lifelong Learning: Uses self-assessment approaches to evaluate professional performance, identifies areas needing improvement, determines learning needs, and organizes personal learning processes to enhance professional knowledge and skills.	-	-	-	-	-